Short-Term Echocardiographic Evaluation by Global Longitudinal Strain in Patients with Heart Failure Treated with Sacubitril/Valsartan

Articles in Press

Document Type : Original Article

Authors

1 Professor of Cardiovascular Medicine, Faculty of Medicine, Benha University

2 Professor of Cardiovascular Medicine Faculty of Medicine - Benha University

3 Professor of Cardiovascular Medicine, Faculty of Medicine Tanta University

4 Department of Cardiology Faculty of Medicine - Benha University

5 Lecturer of Cardiovascular Medicine Faculty of Medicine – Benha University

Abstract

Background: Heart failure (HF) is a clinical syndrome characterized by dyspnea, easy fatigability, and fluid retention. This study aimed to assess the effects of ARNI on GLS and myocardial mechanics in patients with HFrEF. Methods: This prospective observational study that included 50 Patients diagnosed with heart failure. All studied cases were subjected to the following: 12-Lead ECG, laboratory investigations [Baseline Serum creatinine (with eGFR calculation using Cockcroft- Gault equation), serum electrolytes, complete blood count, liver function tests and NT-proBNP, Serum creatinine, eGFR calculation and serum electrolytes.], conventional Echo Doppler Study, 2D Speckle tracking Global Longitudinal Strain and medication management. Results: LVEF and peak GLS were significantly improved at 6 months compared to the baseline measurement (P

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Benha Medical Journal

Articles in Press, Accepted Manuscript
Available Online from 15 November 2024

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