Background: Primary angle-closure glaucoma (PACG) carries a greater risk of causing significant visual impairment compared to primary open-angle glaucoma (POAG). Changes in choroidal thickness (CT) have been implicated in its pathogenesis. Optical coherence tomography (OCT) provides a non-invasive method to evaluate macular choroidal thickness (MCT), which may enhance early detection and risk stratification in patients with narrow-angle conditions. This study aims to investigate and compare MCT in individuals with narrow-angle conditions using OCT. Methods: This case-control study included 75 participants, categorized into three equal groups: Group I (patients with angle-closure glaucoma), Group II (angle-closure suspects), and Group III (healthy controls). CT was assessed in sub-foveal, nasal, and temporal regions utilizing OCT. Results: Sub-foveal, nasal, and temporal choroidal thicknesses were considerably greater in Groups I and II compared to Group III (p < 0.001), with no notable differences observed between Groups I and II. Sub-foveal CT demonstrated a positive correlation with intraocular pressure (IOP) (r = 0.475, p = 0.017) and a negative correlation with spherical equivalent (SE) (r = -0.428, p = 0.033). Temporal CT showed a significant positive correlation with age (r = 0.603, p = 0.001) and best-corrected visual acuity (BCVA) (r = 0.444, p = 0.026). Conclusion: Increased MCT, particularly in sub-foveal, nasal, and temporal regions, may serve as an indicator for angle-closure risk, correlating with elevated IOP and refractive measures. OCT imaging could thus be valuable in early diagnosis and monitoring of angle-closure conditions.
Elsayed, H., El Habbak, A., & Masoud, M. (2025). Measurement of Macular Choroidal Thickness in Narrow Angle Patients by Optical Coherence Tomography. Benha Medical Journal, (), -. doi: 10.21608/bmfj.2025.356921.2319
MLA
Heba Abdelmonem Elsayed; Ashraf Hamed El Habbak; Mohamed Gamal Masoud. "Measurement of Macular Choroidal Thickness in Narrow Angle Patients by Optical Coherence Tomography", Benha Medical Journal, , , 2025, -. doi: 10.21608/bmfj.2025.356921.2319
HARVARD
Elsayed, H., El Habbak, A., Masoud, M. (2025). 'Measurement of Macular Choroidal Thickness in Narrow Angle Patients by Optical Coherence Tomography', Benha Medical Journal, (), pp. -. doi: 10.21608/bmfj.2025.356921.2319
VANCOUVER
Elsayed, H., El Habbak, A., Masoud, M. Measurement of Macular Choroidal Thickness in Narrow Angle Patients by Optical Coherence Tomography. Benha Medical Journal, 2025; (): -. doi: 10.21608/bmfj.2025.356921.2319
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